Effect of Perioperative Oral Pregabalin in Total Knee Replacement for Postoperative Pain
Status: Recruiting
Location: See location...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
This interventional randomized control trial aim to determine efficacy and safety of Oral pregabalin in improving after surgery pain control in patients undergoing total knee replacement surgeries under regional anesthesia. We'll compare the efficacy of pregabalin between two groups, pregabalin group and control group on the basis of their opioid consumption after knee operation.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:
• Age between 18 to 85 year
• Elective Regional anesthesia.
• Able to follow study protocol
Locations
Other Locations
Bahrain
Bahrain Defence Force
RECRUITING
Manama
Contact Information
Primary
MEHTASH BUTT, FCPS,FCAI
dr.mehtashbutt@yahoo.com
+97336681277
Backup
Jalal alkhan, MBBch,FRCA
drjalkhan@gmail.com
+97317766666
Time Frame
Start Date: 2023-09-01
Estimated Completion Date: 2025-07-30
Participants
Target number of participants: 120
Treatments
Active_comparator: Pregabalin group
this group of patient will receive cap pregabalin 75mg as premedication and will continue as twice daily dose for 72 hrs.
Sham_comparator: Control group
This group of patient will not receive cap pregabalin but it will receive standard medical care as routine
Related Therapeutic Areas
Sponsors
Leads: Bahrain Defence Force Hospital